Profhilo® Structura

PROFHILO® STRUCTURA is a cutting-edge injectable bioremodeling procedure that targets superficial fat compartments to rejuvenate, lift, and contour the face. STRUCTURA provides a natural, regenerative solution to midface aging by regenerating facial fat tissue, as opposed to volumizing like traditional dermal fillers do.

NAHYCO® hybrid cooperative complexes of low and high molecular weight hyaluronic acid, which are specifically made to restore adipose tissue homeostasis, are used in the formulation of this product. It is perfect for patients looking for genuine aesthetic enhancements because it offers minimally invasive, yet profound, improvements in facial structure.

PROFHILO® STRUCTURA's distinct composition, targeting action, and potent clinical performance set it apart in the regenerative aesthetics market.

includes two millilitres of 90 mg of ultrapure hyaluronic acid (45 mg high MW and 45 mg low MW).

produced without the use of chemical cross-linking agents and utilizing the patented NAHYCO® thermal technology.

not only for volumization but also for fat restoration when injected into superficial fat layers.

Following the initial treatment, 95% of patients reported observable improvements.

Tissue thickness increased by +23% three months after treatment.

In patients exhibiting signs of aging, PROFHILO® STRUCTURA is recommended for the restoration of superficial facial fat, specifically in the jawline, cheek hollows, and midface. It is appropriate for people who have lost fat as a result of aging or who have lost weight quickly (for example, from using GLP-1 products like Ozempic®).

Clinical Significance:

• Loss of volume in the middle
• facial angle flattening
• Laxity and sagging in the jaw or cheek region
• restoration of the proportions of a youthful face

Contraindications:

• Infections or inflammatory skin disorders that are active at the treatment site
• Hyaluronic acid hypersensitivity
• Breastfeeding or pregnancy
• Side effects that have been reported:
• Reports of minimal downtime
• Possible minor bruising, swelling, or redness at the injection sites
• Use of cannulas is linked to a 77.1% decreased incidence of vascular occlusion events.

In the formulation of PROFHILO® STRUCTURA, low molecular weight HA (80–100 kDa) and high molecular weight HA (1100–1400 kDa) are combined in hybrid cooperative complexes (HCCs). Without the need for chemical stabilizers, this formulation guarantees tissue integration, deep biocompatibility, and sustained activity.

Packing:

• One pre-filled 2 mL syringe
• Two 22G x 50mm and 25G x 38mm TSK cannulas
• Two 21G x 25mm and 23G x 19mm pilot needles
• Included are patient leaflets and implant cards.

Make-up:

• 90 mg of HA in total per syringe
• pH-regulated, ultra-pure mixture
• No cross-linking agents or BDDE
• Perfect for applications involving bioregeneration

PROFHILO® STRUCTURA is administered by qualified professionals into the superficial fat layer, specifically targeting sagging or hollow regions of the midface. The treatment typically follows a two-session protocol, spaced 30 days apart, with minimal discomfort or downtime.

Administration Protocol:

• Injection site: Preauricular region (upper cheek), targeting superficial fat
• Injection technique: Cannula method preferred to reduce vascular risk
• Volume: 2 mL per session (1 syringe)
• Treatment schedule: 2 sessions, 1 month apart
• Post-treatment: No massage needed; patients can resume daily activities

Expected Results:

• +23% increase in tissue thickness observed via clinical imaging
• Improvements in skin firmness, midface projection, and facial angles
• High patient satisfaction (95%) sustained at 3 months post-treatment